COMMITTEE OF AUTOANTIBODY
STANDARDIZATION INTERNATIONAL
UNION OF IMMUNOLOGICAL SOCIETIES (AutoAb.org)

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ACR Study Group 2009

Autoantibodies in Diagnosis and Follow-up of Rheumatic Diseases
Coordinators:  Angela Tincani, MD, and Edward K.L. Chan, PhD
Moderator: Pier Luigi Meroni, MD

Session Objectives:
identify the common clinical problems associated with inaccurate ANA results
describe the current technologies that clinical laboratories are using and how physicians should be engaged with the clinical laboratory
outline the proper use and interpretation of autoantibody testing in a clinical rheumatology setting
state the role and ethical obligations of the manufacturer, diagnostic laboratory and the clinician in the production, sale and use of autoantibody diagnostic kits
 

Introduction
by Pier Luigi Meroni, MD, Milan, Italy

pdf file 61kB

Cases of Inaccurate ANA
by Merlin R. Wilson, MD, New Orleans, LA
pdf file 3.9MB

Screening ANA Assays: Immunofluorescence on HEp-2 cells vs Enzyme Immunoassays and Multiplex Bead Assays
by Eng M. Tan, MD, La Jolla, CA
pdf file 1.4MB

Algorithm for ANA Testing and Interpretation
by Luis Eduardo C. Andrade, MD, PhD, Sao Paulo, Brazil
pdf file 1.5MB

Role of FDA on ANA Testing
by Marilyn Lightfoote, PhD, FDA, Rockville, MD

Overall Summary of Study Group 34kB

11/2009