Edward K. L. Chan

 
Reviews & Chapters:
Pauley, K.M. and Chan, E.K.L.  (2008)  MicroRNAs and their emerging roles in immunology.  In: Noel R. Rose (ed), The Year in Immunology, Annals of the New York Academy of Sciences, in press.
Satoh, M., Chan, E.K.L., Sobel, E.S., Kimpel, D.L., Yamasaki, Y., Narain, S., Mansoor, R., and Reeves, W.H. (2007)  Clinical implication of autoantibodies in patients with systemic rheumatic diseases.  Expert Rev. Clin. Immunol. 3:721-738.
Fritzler, M.J., Stinton, L.M., and Chan, E.K.L. (2007)  Autoantibodies to cytoplasmic autoantigens in endosomes, exosomes and the Golgi complex.  In: Conrad K, Chan, EKL, Fritzler MJ, Sack U, Shoenfeld Y, Wiik A (eds), From Etiopathogenesis to the Prediction of Autoimmune Diseases: Relevance of Autoantibodies. Autoantigens, Autoantibodies and Autoimmunity series. Proceedings 8th Dresden Symposium on Autoantibodies.  Pabst Science Publishers, Lengerich, Germany. Chapter 4, pp. 194-209.
Ikeda, K., Pauley, K.M., Jakymiw, A., Satoh, M., Fritzler, M.J., and Chan, E.K.L. (2007)  Autoantibodies to key components of RNA interference pathway.  In: Conrad K, Chan, EKL, Fritzler MJ, Sack U, Shoenfeld Y, Wiik A (eds), From Etiopathogenesis to the Prediction of Autoimmune Diseases: Relevance of Autoantibodies. Autoantigens, Autoantibodies and Autoimmunity series. Proceedings 8th Dresden Symposium on Autoantibodies.  Pabst Science Publishers, Lengerich, Germany. pp. 168-177.
Jakymiw, A., Pauley, K.M., Li, S., Lian, S., Ikeda, K., Eystathioy, T., Satoh, M., Fritzler, M.J., and Chan, E.K.L. (2007) The role of GW/P-bodies in RNA processing and silencing.  J. Cell Sci., 120:1317-23.  A commissioned commentary. PubMed abstract.
Chan, E.K.L., Peebles, C., Fritzler, M.J., and Satoh, M. (2007)  Anti-spliceosomal autoantibodies.  In Systemic Lupus Erythematosus: A Companion to Rheumatology, edited by George C. Tsokos, Caroline Gordon, and Josef S. Smolen.  Elsevier Science, San Diego, CA, Chapter 22G.
Chan, E.K.L. (2006) Autoantibodies and the cloning and characterization of cellular constituents.  In Autoantibodies and Autoimmunity: Molecular Mechanisms in Health and Disease.  Edited by K. Michael Pollard, Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany, Chapter 18, pp419-446. (606kB)
Chan, E.K.L., Burlingame, R.W., and Fritzler, M.J. (2006)  Detection of autoantibodies using immobilized natural and recombinant autoantigens.  In Manual of Molecular and Clinical Laboratory Immunology, 7th ed. edited by Detrick, B., Hamilton, R.G., Folds, J.D.,  American Society for Microbiology Press, Washington, D.C. Chapter 114, pp1019-1026.
Chan, E.K.L.  (2006)  Ninth International Workshop on Autoantibodies and Autoimmunity, Gainesville, Florida.  Special issue edited with an editorial, Autoimmunity Reviews, Volume 5, Issue 4, 12 articles. 
Chan, E.K.L., Peebles, C., Fritzler, M.J., and Satoh, M. (2006)  Anti-spliceosomal autoantibodies.  In Systemic Lupus Erythematosus: A Companion to Rheumatology, edited by George C. Tsokos, Caroline Gordon, and Josef S. Smolen.  Elsevier Science, San Diego, CA, Chapter 3G.
Fritzler, M.J., and Chan, E.K.L.  (2006)  Golgi complex and endosome antibodies.  In Autoantibodies, 2nd edition, edited by Shoenfeld, Y., Gershwin, M.E., and Meroni, P.L.  Elsevier Science, Chapter 35, pp263-270.
Fritzler, M.J., and Chan, E.K.L.  (2006)  GW bodies, P bodies and components of the microRNA pathway.  In Autoantibodies, 2nd edition, edited by Shoenfeld, Y., Gershwin, M.E., and Meroni, P.L.  Elsevier Science, Chapter 34, pp257-262.
Nozawa, K., Fritzler, M.J., and Chan, E.K.L.  (2005)  Unique and shared features of Golgi complex autoantigens. Autoimmunity Reviews.  4:35-41. (pdf 176kB)
Zhang, J.Y. and Chan, E.K.L. (2005)  Tumor specific autoimmune responses - Why and when do they develop?  In Methods, Possibilities and Perspectives of Pre-symptomatic Tumor Diagnostics.  Edited by Conrad, K., Sack, U., and Bachmann, M. Pabst Scientific Publishers, Lengerich, Germany, pp35-42.
Fritzler, M.J. and Chan, E.K.L. (2004) Antibodies to nonhistone antigens in systemic lupus erythematosus.  In Systemic Lupus Erythematosus, 4th ed. edited by Robert G. Lahita, Elsevier Science, San Diego, Chapter 13, p349-376. 
Stinton, L.M., Eystathioy, T., Selak, S., Chan, E.K.L., and Fritzler, M.J.  (2004) Autoantibodies to protein transport and messenger RNA processing pathways:  endosomes, lysosomes, Golgi complex, proteasomes, assemblyosomes, exosomes and GW bodies.  Clin. Immunol. 110:30-44.
Chan, E.K.L. (2004)  Autoantibody target GW bodies – cytoplasmic foci of mRNA decay and regulatory functions.  In Autoantigens, Autoantibodies, Autoimmunity, Volume 5, Pabst Scientific Publishers, Lengerich, Germany, p203-208.
Zhang, J.Y. and Chan, E.K.L. (2002) Autoantibodies to IGF-II mRNA binding protein p62 and overexpression of p62 in human hepatocellular carcinoma.  Autoimmunity Reviews 1: 146-153.
Chan, E.K.L., Himoto, T., and Zhang, J.Y.  (2002) Autoantibodies in liver diseases and hepatocellular carcinoma.  In Liver Immunology, edited by M. Eric Gershwin, John M. Vierling, and Michael P. Manns, Hanley and Belfus, Inc., Philadelphia, Chapter 12, p151-169.
Fritzler, M.J. and Chan, E.K.L. (2000)  Autoantibodies to Endosomes and the Golgi Complex.  In Autoantigens, Autoantibodies, and Autoimmunity edited by Conrad, K., Humbel, R-L., Meurer, M., Shoenfeld, Y., Tan, E.M., Vol. 1, Autoantigens and autoantibodies: diagnostic tools and clues to understanding autoimmunity. Pabst Scientific Publishers, Lengerich, Germany. p339-361.
Chan, E.K.L. and Fritzler, M.J. (1998) Golgins: coiled-coil proteins associated with the Golgi Complex.  Electronic Journal of Biotechnology. 1998 Vol. 1(2) Available from http://www.ejbiotechnology.info/content/vol1/issue2/full/1/index.html
Chan, E.K.L. and Tan, E.M. (1997)  Human antibodies and characterization of their target antigens.  Cells: A Laboratory Manual, edited by Spector, D.S., Goldman, R., Leinwand, L. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York.  Chapter 74.
Chan, E.K.L. and Pollard, K.M. (1997)  Detection of autoantibodies to ribonucleoprotein particles by immunoblotting.  In Manual of Clinical Laboratory Immunology, 5th ed. edited by Rose, N.R., Conway de Macario, E., Folds, J.D., Lane, H.C., and Nakamura, R.M.  American Society for Microbiology Press, Washington, D.C., Chapter 115, p928-934.

update 6/2008